MEG-01（人慢性粒细胞性白血病细胞）
CBP61104
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| I. General information | |
| Synonyms: | MEG-01 |
| Background: | The MEG-01 cell line was derived in 1983 at the Nagoya University School of Medicine, Nagoya, Japan from bone marrow cells taken from a patient in megakaryoblastic crisis of CML. |
| Species: | Homo sapiens, human |
| Tissue: | bone marrow |
| Disease: | chronic myelogenous leukemia (CML) |
| Gender: | male,55 years |
| Morphology: | lymphoblast |
| Growth Mode: | mixed, adherent and suspension |
| Doubling Time: | 36 to 48 hrs |
| DNA Profile: | Amelogenin: X,Y CSF1PO: 10 D13S317: 8 D16S539: 9 D5S818: 13 D7S820: 11 THO1: 7 TPOX: 8,11 vWA: 16 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI-1640+10%FBS MEG-01完全培养基，# CBP61104M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | CD41 +; CD61 +; CDw14 + |
| Receptor Expression: | N/A |
| Oncogene: | N/A |
| Genes Expressed: | N/A |
| Cellular Products: | N/A |
| Tumor Formation: | N/A |
| Comments: | The cells are positive for cytoplasmic Factor VIII and surface GPIIb/IIIa, periodic acid - Schiff (PAS) reaction, alpha naphthyl acetate esterase and acid phosphatase. They are negative for myeloperoxidase, alpha naphthyl butyrate esterase, naphthol AS-D chloroacetate esterase and alkaline phosphatase. The stain positively with monoclonal antibodies BA-1 (anti B cell, granulocyte), HPL-3 (anti gpIIb/IIIa) and 20.3 (anti monocyte, platelet). They are negative for other lymphoid and myeloid seris antigens. For more information, please contact Cobioer (4008-750-250). |
