ARH-77（人白血病肿瘤细胞）
CBP60516
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| I. General information | |
| Synonyms: | ARH-77 |
| Background: | The ARH-77 cell line was established from the peripheral blood of a patient suffering from IgG plasma cell leukemia. Although established from cells taken from a patient with a plasma cell leukemia, this line has been shown to be an EBV-transformed B lymphoblastoid cell line. |
| Species: | Homo sapiens, human |
| Tissue: | peripheral blood |
| Disease: | plasma cell leukemia |
| Gender: | Caucasian,female, 33 years |
| Morphology: | lymphoblast |
| Growth Mode: | suspension |
| DNA Profile: | D5S818: 10,13 D13S317: 11,13 D7S820: 7,12 D16S539: 9,13 vWA: 17 THO1: 8,9.3 Amelogenin: X TPOX: 8 CSF1PO: 6,10 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI1640+10%FBS ARH-77完全培养基，# CBP60516M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | CD11a +; CD19 +; CD20 +; CD28 +; CD38 -; CD49e + |
| Comments: | The cells are positive for Epstein-Barr nuclear antigen(EBNA +) and Epstein-Barr viral capsid antigen (EBVCA +). The line has been cured of a previous mycoplasma infection.LICR-LON-HMy2 (HMy2), a fast growing mutant of the ARH-77 cell line (ATCC CRL-1621), was irradiated and selected for class I loss to establish the HMy2.C1R (ATCC CRL-1993) cell line. Subsequently, C1R-neo (ATCC CRL-2369), C1R-sB7 (ATCCCRL-2370), and C1R-B7 (ATCC CRL-2371) were established by transfection of the HMy2.C1R cell line. For more information, please contact Cobioer (4008-750-250). |
