ME180（人子宫颈鳞状癌细胞）
CBP60645
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| I. General information | |
| Synonyms: | ME180 |
| Background: | This line was derived from a highly invasive squamous cell carcinoma with irregular cell clusters and no significant keratinization. |
| Species: | Homo sapiens, human |
| Tissue: | cervix; derived from metastatic site: omentum |
| Disease: | epidermoid carcinoma |
| Gender: | Caucasian,female,66 years |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| DNA Profile: | Amelogenin: X CSF1PO: 11 D13S317: 11,13 D16S539: 12,13 D5S818: 12 D7S820: 9,10 THO1: 8,9.3 TPOX: 8,10 vWA: 15,17 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
McCoy's 5a+10%FBS ME180完全培养基，# CBP60645M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | Blood Type A; Rh+; HLA A1, A11, B5(+/-), B40 |
| Oncogene: | p53 +; pRB + |
| Genes Expressed: | N/A |
| Tumor Formation: | Yes, in nude mice; forms well differentiated epidermoid carcinoma (grade I) |
| Comments: | Desmosomal attachments were observed between cells in monolayer culture and cytoplasmic tonofilaments were noted. Contamination with Mycoplasma arginini was detected and eliminated in 1970. Growth of ME-180 cells is inhibited by tumor necrosis factor alpha (TNF alpha).The cells contain human papillomavirus (HPV) DNA with greater homology to HPV-68 than HPV-18. For more information, please contact Cobioer (4008-750-250). |
