CXCR5/β-Arrestin/CHO
CBP71398
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I. Background | |
CXCR5 (C-X-C Motif Chemokine Receptor 5) is a Protein Coding gene. Diseases associated with CXCR5 include Intraocular Lymphoma and Lymphoma. Among its related pathways are CCR5 Pathway in Macrophages and Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and C-X-C chemokine receptor activity. | |
II. Introduction | |
Host Cell: |
CHO |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12k+10%FBS+5ug/ml puromycin+5ug/ml blasticidin |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): |
Functional assay for CXCR5 |
Transducer: | β-arrestin |
Ⅲ. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data | |
Figure 1. Recombinant CXCR5/β-Arrestin/CHO constitutively expressing CXCR5. |
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Figure 2.Dose response of Human CXCL13 in CXCR5 β-Arrestin CHO-K1 Cell Line (C25). |