CRTH2(DP2)/CHO
CBP71380
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I. Background | |
CRTH-2 is a 7-transmembrane G-protein coupled receptor that is expressed by activated Th2 cells and eosinophils. | |
II. Introduction | |
Host Cell: |
CHO |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12K+10%FBS+5ug/ml puromycin |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): |
Functional assays for CRTH2 |
Transducer: | Gi |
Ⅲ. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data | |
Figure 1. Recombinant CRTH2(DP2)/CHO constitutively expressing CRTH2(DP2). |
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Figure 2. HTRF CAMP Assay with CRTH2(DP2) CHO Cells (C1). |