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ERBB2 p.V777M Reference Standard

CBP10273

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Introduction 
Format Genomic DNA
Description ERBB2 (HER2) V777M lies within the protein kinase domain of the Erbb2 (Her2) protein (UniProt.org). V777M has been identified in the scientific literature (PMID: 22761469, PMID: 28481359, PMID: 27284958), but has not been biochemically characterized and therefore, its effect on Erbb2 (Her2) protein function is unknown (PubMed, Sep 2018).
   
Technical Data 
DNA Change c.2329G>A
AA Change p.V777M
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 50.00%
Transcript ENST00000269571
Cosmic ID COSM14064
Chr position(GRCh37) chr17:37881000
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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