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ERBB2 p.R1230fs Reference Standard

CBP10501

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索取COA
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产品数据库
Introduction 
Format Genomic DNA
Description ERBB2 (HER2), erb-b2 receptor tyrosine kinase 2, is an EGFR receptor tyrosine kinase that activates PI3K-AKT-mTOR and RAS-RAF-MEK-ERK pathways, therefore regulating growth and transformation (PMID: 17471238). ERBB2 (HER2) amplification, overexpression, and activation has been implicated in several tumor types (PMID: 17471238).
   
Technical Data 
DNA Change c.3688delG
AA Change p.R1230fs
Mutation type N/A
Zygosity Heterozygous
Allelic Frequency  20%
Transcript N/A
Cosmic ID N/A
Chr position(GRCh37) chr17:37884218
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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