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AI-Edigene® ERBB2 p.V777_G778insCG Reference Standard Plus

CBP10474

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索取COA
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产品数据库
Introduction 
Gene ERBB2
Description ERBB2 (HER2), erb-b2 receptor tyrosine kinase 2, is an EGFR receptor tyrosine kinase that activates PI3K-AKT-mTOR and RAS-RAF-MEK-ERK pathways, therefore regulating growth and transformation (PMID: 17471238). ERBB2 (HER2) amplification, overexpression, and activation has been implicated in several tumor types (PMID: 17471238).
   
Technical Data 
DNA Change c.2331_2332insTGTGGG
AA Change p.V777_G778insCG
Mutation type In_Frame_Ins
Zygosity Homozygous
Allelic Frequency 100%
Transcript NM_004448.3
Cosmic ID N/A
Chr position(GRCh37) chr17:37881002_37881003
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

 

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