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AI-Edigene® ERBB2 p.V777L Reference Standard Plus

CBP10433

询 价
索取COA
产品描述
产品数据库
Introduction 
Gene ERBB2
Description ERBB2 (HER2) V777L lies within the protein kinase domain of the Erbb2 (Her2) protein (UniProt.org). V777L results in increased Erbb2 (Her2) activity, increased downstream Mapk pathway activation, increased ability to transform cells in culture (PMID: 29967253), and increased tumor growth in xenograft models (PMID: 23220880)
   
Technical Data 
DNA Change c.2329G>T
AA Change p.V777L
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript NM_004448.3
Cosmic ID COSM14062
Chr position(GRCh37) chr17:37881000
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

 

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