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TP53 p.G389W Reference Standard

CBP10529

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索取COA
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Introduction 
Format Genomic DNA
Description TP53, tumor protein p53, is a tumor suppressor (PMID: 30562755) and oncogene (PMID: 30577483) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457).
   
Technical Data 
DNA Change c.1165G>T
AA Change p.G389W
Mutation type Missense_Mutation
Zygosity Heterozygous
Allelic Frequency 50%
Transcript ENST00000269305.4
Cosmic ID N/A
Chr position(GRCh37) chr17:7572944
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8°C
Expiry 36 months from the date of manufacture

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