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TP53 p.G266E Reference Standard

CBP10174

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Introduction 
Format Genomic DNA
Description TP53 G266E lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). G266E results in decreased Tp53 transactivation activity (PMID: 20505364), and has been shown to promote cell motility in culture (PMID: 22114072).
   
Technical Data 
DNA Change c.797G>A
AA Change p.G266E
Mutation type Substitution - Nonsense
Zygosity Heterozygous
Allelic Frequency 50%
Transcript ENST00000269305
Cosmic ID COSM10867
Chr position(GRCh37) chr17:7577141
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8℃
Expiry 36 months from the date of manufacture

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