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TP53 p.C135Y Reference Standard

CBP10168

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索取COA
产品描述
产品数据库
Introduction 
Format Genomic DNA
Description TP53 C135Y lies within the DNA-binding domain of the Tp53 protein (UniProt.org). C135Y confers a loss of function to the Tp53 protein as demonstrated by loss of binding to the Drosha complex and inability to induce downstream miRs and loss of transactivation activity in cell culture (PMID: 19626115, PMID: 8336941).
   
Technical Data 
DNA Change c.404G>A
AA Change p.C135Y
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000269305
Cosmic ID COSM10801
Chr position(GRCh37) chr17:7578526
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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