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PIK3CA p.E545G Reference Standard

CBP10543

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索取COA
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产品数据库
Introduction 
Format Genomic DNA
Description PIK3CA E545G is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E545G confers a gain of function on the Pik3ca protein as demonstrated by increased phosphorylation of Akt and transFormation in cell culture (PMID: 17376864, PMID: 29533785).
   
Technical Data
DNA Change: c.1634A>G
AA Change p.E545G
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 50%
Transcript NM_006218
Cosmic ID COSM764
Chr position(GRCh37) chr3:178936092
Buffer: Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8°C
Expiry 36 months from the date of manufacture

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