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PIK3CA p.E453K Reference Standard

CBP10332

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索取COA
产品描述
产品数据库
Introduction 
Format Genomic DNA
Description PIK3CA E453K lies within the C2 PI3K-type domain of the Pik3ca protein (UniProt.org). E453K results in increased phosphorylation of Akt and Mek1/2, enhanced cell survival, and is transforming in culture (PMID: 26627007, PMID: 29533785).
   
Technical Data 
DNA Change c.1357G>A
AA Change p.E453K
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 50.00%
Transcript NM_006218.1
Cosmic ID COSM12584
Chr position(GRCh37) chr3:178928079
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture
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