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AI-Edigene® PIK3CA p.E545K Reference Standard Plus

CBP10517

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索取COA
产品描述
产品数据库
Introduction 
Format Genomic DNA
Description PIK3CA E545K is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E545K results in increased phosphorylation of Akt and Mek1/2, growth factor-independent cell survival, and is transforming in culture (PMID: 26627007, PMID: 29533785).
   
Technical Data 
DNA Change c.1633G>A
AA Change p.E545K
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100.00%
Transcript NM_006218.4
Cosmic ID COSM763
Chr position(GRCh37) chr3:178936091
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8°C
Expiry 36 months from the date of manufacture

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