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PIK3CA p.E545A Reference Standard

CBP10323

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索取COA
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产品数据库
Introduction 
Format Genomic DNA
Description PIK3CA E545A is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E545A confers a gain of function on the Pik3ca protein as demonstrated by increased phosphorylation of Akt and transFormation in cell culture (PMID: 17376864, PMID: 29533785).
   
Technical Data 
DNA Change c.1634A>C
AA Change p.E545A
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 50%
Transcript NM_006218.1
Cosmic ID COSM12458
Chr position(GRCh37) chr3:178936092
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture
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