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TP53 p.P278H Reference Standard

CBP10202

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Introduction 
Format Genomic DNA
Description TP53 P278H lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). P278H has been identified in sequencing studies (PMID: 25151357), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Oct 2018).
   
Technical Data 
DNA Change c.833C>Ap
AA Change p.P278H
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 66.67%
Transcript ENST00000269305
Cosmic ID COSM43755
Chr position(GRCh37) chr17:7577105
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8
Expiry 36 months from the date of manufacture

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