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EGFR p.A289D Reference Standard

CBP10265

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索取COA
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Introduction 
Format Genomic DNA
Description EGFR A289D lies within the extracellular domain of the Egfr protein (PMID: 22588883). A289D confers a gain of function on Egfr protein, as indicated by increased Egfr phosphorylation (PMID: 22588883) and increased cell proliferation and viability in culture (PMID: 29533785).
   
Technical Data 
DNA Change c.866C>A
AA Change p.A289D
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 33.33%
Transcript ENST00000275493
Cosmic ID COSM21685
Chr position(GRCh37) chr7:55221822
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8℃
Expiry 36 months from the date of manufacture
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