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AI-Edigene® EGFR p.C797S Reference Standard Plus

CBP10341

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索取COA
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产品数据库
Introduction 
Format Genomic DNA
Description EGFR C797S lies within the ATP-binding pocket in the protein kinase domain of the Egfr protein (PMID: 25964297). C797S has been demonstrated to confer resistance to third-generation EGFR inhibitors (PMID: 25964297, PMID: 25948633, PMID: 29410323), but has not been biochemically characterized and therefore, its effect on Egfr protein function is unknown (PubMed, Jun 2018).
   
Technical Data 
DNA Change: c.2389T>A
AA Change p.C797S
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 50%
Transcript ENST00000275493
Chr position(GRCh37) COSM6493937
Chr position(GRCh37) chr7:55249091
Buffer: Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1µg
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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