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AI-Edigene® EGFR p.E709A Reference Standard Plus

CBP10512

询 价
索取COA
产品描述
产品数据库
Introduction 
Format Genomic DNA
Description  EGFR (HER1), epidermal growth factor receptor, is a tyrosine kinase receptor, which activates RAS/RAF/MEK and PI3K/AKT/mTOR pathways, leading to increased cell proliferation and growth (PMID: 24312144). EGFR activating mutations, amplification, and overexpression are found in a variety of tumors, including non-small cell lung cancer (PMID: 26609494, PMID: 30284706) and colorectal cancer (PMID: 30243897), and the EGFRvIII variant is commonly found in glioblastoma (PMID: 30201736).
   
Technical Data 
DNA Change: c.2126A>C
AA Change p.E709A
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 100%
Transcript ENST00000275493
Cosmic ID COSM13427
Chr position(GRCh37) chr7:55241678
Buffer: Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1µg
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

 

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诊断标准品联系方式: 华东销售经理:15000320447 华北销售经理:18131625521 华南销售经理:13484295986 华中&西南销售经理:13871580511 全国销售经理:13484295986

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