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TP53 p.Y163C Reference Standard

CBP10160

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索取COA
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产品数据库
Introduction 
Format Genomic DNA
Description TP53 Y163C lies within the DNA binding domain of the Tp53 protein (PMID: 22713868). Y163C results in decreased transactivation of Tp53 target genes, increased cellular growth rate, and failure to induce apoptosis in cell culture (PMID: 23246812).
   
Technical Data 
DNA Change: c.488A>G
AA Change p.Y163C
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000269305
Cosmic ID COSM10808
Chr position(GRCh37) chr17:7578442
Buffer: Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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