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TP53 p.V216M Reference Standard

CBP10192

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Introduction 
Format Genomic DNA
Description TP53 V216M lies within the DNA-binding domain of the Tp53 protein (UniProt.org). V216M results in decreased Tp53 transactivation activity in cultured cells (PMID: 20505364), and is therefore predicted to confer a loss of function to the Tp53 protein.
   
Technical Data 
DNA Change c.646G>A
AA Change p.V216M
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 97.75%
Transcript ENST00000269305
Cosmic ID COSM10667
Chr position(GRCh37) chr17:7578203
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8℃
Expiry 36 months from the date of manufacture

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