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TP53 p.S241F Reference Standard

CBP10194

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Introduction 
Format Genomic DNA
Description TP53 S241F lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). S241F results in a decreased in Tp53 transcriptional activity (PMID: 19225112, PMID: 26585234), and interferes with Formation of the Tp53/Bard1/CstF complex in cell culture (PMID: 21383700).
   
Technical Data 
DNA Change c.722C>T
AA Change p.S241F
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000269305
Cosmic ID COSM10812
Chr position(GRCh37) chr17:7577559
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture
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