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TP53 p.S215I Reference Standard

CBP10206

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Introduction 
Format Genomic DNA
Description TP53 S215I lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). S215I is predicted to confer a loss of function to the Tp53 protein, as demonstrated by the inability to transactivate Mdm2 in-vitro (PMID: 17325666).
   
Technical Data 
DNA Change c.644G>T
AA Change p.S215I
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000269305
Cosmic ID COSM11450
Chr position(GRCh37) chr17:7578205
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8
Expiry 36 months from the date of manufacture

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