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TP53 p.R213* Reference Standard

CBP10181

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Introduction 
Format Genomic DNA
Description TP53 R213* results in a premature truncation of the Tp53 protein at amino acid 213 of 393 (UniProt.org). Due to the loss of the much of the DNA binding domain, as well as the tetramerization domain and C-terminal basic domain, R213* is predicted to result in a loss of Tp53 protein function (PMID: 20978130).
   
Technical Data 
DNA Change c.637C>T
AA Change p.R213*
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000269305
Cosmic ID COSM10654
Chr position(GRCh37) chr17:7578212
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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