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TP53 p.H193R Reference Standard

CBP10147

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Introduction 
Format Genomic DNA
Description TP53 H193R lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). H193R has not been biochemically characterized in human cells, but results in decreased Tp53 transactivation ability in yeast assays and is predicted to result in decreased Tp53 stability and protein expression by computational modeling (PMID: 9627118, PMID: 21763698).
   
Technical Data 
DNA Change: c.578A>G
AA Change p.H193R
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000269305
Cosmic ID COSM10742
Chr position(GRCh37) chr17:7578271
Buffer: Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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