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TP53 p.E286K Reference Standard

CBP10205

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Introduction 
Format Genomic DNA
Description TP53 E286K lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). E286K results in decreased transactivation activity in cultured cells (PMID: 20505364), and is therefore predicted to result in a loss of Tp53 protein function.
   
Technical Data 
DNA Change c.856G>A
AA Change p.E286K
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000269305
Cosmic ID COSM10726
Chr position(GRCh37) chr17:7577082
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8
Expiry 36 months from the date of manufacture

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