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TP53 p.C275fs*20 Reference Standard

CBP10163

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Introduction 
Format Genomic DNA
Description TP53 C275* results in a premature truncation of the Tp53 protein at amino acid 275 of 393 (UniProt.org). C275* results in a loss of Tp53 transactivation activity and inability to suppress colony Formation in cell culture (PMID: 25584008).
   
Technical Data 
DNA Change c.822_853del32
AA Change p.C275fs*20
Mutation type Substitution - Missense
Zygosity Heterozygous
Transcript ENST00000269305
Cosmic ID N/A
Chr position(GRCh37) chr17:7577085_7577116
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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