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CTNNB1 p.S37P Reference Standard

CBP10256

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Introduction 
Format Genomic DNA
Description CTNNB1 S37P lies within the ubiquitination recognition motif of the Ctnnb1 protein and occurs at a Gsk3b phosphorylation site on the Ctnnb1 protein (PMID: 10347231). S37P has not been characterized, however other S37 “hotspot” mutations are activating thus, S37P is predicted to result in a gain of Ctnnb1 function (PMID: 9671767, PMID: 10347231).
   
Technical Data 
DNA Change c.109T>C
AA Change p.S37P
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 50.00%
Transcript ENST00000349496
Cosmic ID COSM5687
Chr position(GRCh37) chr3:41266112
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8
Expiry 36 months from the date of manufacture

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