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CTNNB1 p.S33C Reference Standard

CBP10250

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Introduction 
Format Genomic DNA
Description CTNNB1 S33C lies within the ubiquitination recognition motif of the Ctnnb1 protein and occurs at a Gsk3b phosphorylation site on the Ctnnb1 protein (PMID: 15064718). S33C confers a gain of function to the Ctnnb1 protein as demonstrated by nuclear accumulation of Ctnnb1 and increased Ctnnb1-driven transcription (PMID: 10076565, PMID: 21881488, PMID: 19582367).
   
Technical Data 
DNA Change c.98C>G
AA Change p.S33C
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 33.33%
Transcript ENST00000349496
Cosmic ID COSM5677
Chr position(GRCh37) chr3:41266101
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture
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