TM3（小鼠睾丸间质细胞）
CBP60901
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| I. General information | |
| Synonyms: | TM3 |
| Species: | Mus musculus, mouse |
| Tissue: | testis |
| Gender: | male, 11 to 13 days |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| Culture Medium: |
F12:DMEM(1:1)+0.5mM NaP+5%HS+2.5%FBS TM3完全培养基，# CBP60901M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Receptor Expression: | luteinizing hormone (LH); epidermal growth factor (EGF); androgen receptor, positive; estrogen receptor, positive; progesterone receptor, positive |
| Genes Expressed: | prostaglandin F2a |
| Tumor Formation: | No, The cells were not tumorigenic in immunosuppressed mice, but did form colonies in semisolid medium. |
| Comments: | The TM3 cell line responds to LH with an increase in cAMP production, but does not respond to follicle stimulating hormone (FSH). The maintenance of responsiveness to LH is dependent upon serum lot. In the presence of LH, the cells are capable of metabolizing cholesterol. Tested and found negative for ectromelia virus (mousepox). For more information, please contact Cobioer (4008-750-250). |
