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CCDC6-RET WT/BaF3

CBP73214

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I. Introduction
Cell Line Name: CCDC6-RET WT/BaF3
Host Cell: BA/F3
Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Application: Anti-proliferation assay and PD assay
Freeze Medium: 90% FBS+10% DMSO
Complete Culture Medium: RPMI-1640+10%FBS+1ug/ml puromycin
Mycoplasma Status: Negative
 
II. Background

CCDC6, coiled-coil domain containing 6, has been shown to play a role in the DNA damaging signaling pathway acting as a substrate of ATM (PMID: 17420723). CCDC6 fusions with RET (PMID: 23154560, PMID: 26078337) and BRAF (PMID: 26314551) have been observed in multiple cancer types.

 
III. Representative Data

1. WB of  CCDC6-RET WT/BaF3WT 

2. Sanger of CCDC6-RET WT/BaF3

Figure 2. Breakpoint of CCDC6-RET WT/BaF3

2. Anti-proliferation assay

Figure 3. CTG assay of  for CCDC6-RET WT/BaF3 Stable Cell Line,the Gi50 was 137.3nM.

药靶模型联系方式: 华东销售经理:18240630236 全国销售经理:18066071954
诊断标准品联系方式: 华东销售经理:15000320447 华北销售经理:18131625521 华南销售经理:13484295986 华中&西南销售经理:13871580511 全国销售经理:13484295986

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