TSHR CHO
CBP71474
询 价
索取Protocol
产品描述
产品数据库
| I. Background | |
|
TSHR (Thyroid Stimulating Hormone Receptor) is a Protein Coding gene. Diseases associated with TSHR include Hypothyroidism, Congenital, Nongoitrous, 1 and Hyperthyroidism, Familial Gestational. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling. |
|
| II. Description | |
|
TSHR CHO 报告基因药靶模型很好的模拟了体内 TSHR 的信号转导过程，原理见下图所示。 |
|
| Figure 1. TSHR CHO 细胞模型原理图
|
|
| III. Introduction | |
| Expressed gene: | TSHR |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+5μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional assay for TSHR receptor |
| Transducer: | Gs |
IV. Representative Data Figure 2. Recombinant TSHR CHO stably expressing TSHR.  |
|
|
Figure 3. HTRF cAMP Assay with TSHR CHO(C11). Figure 4. HTRF cAMP Assay with TSHR CHO(C11). |
|
