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GITRL/CHO

CBP74094

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I. Background
GITRL (CD357; AITRL; TNLG2A), a part of the tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18), is mainly expressed on antigen presenting cells. GITRL engages with the GITR receptor as a co-stimulatory signal to promote lymphocyte activation.
 
II. Description

Recombinant CHO cell constitutively expressing full length human GITRL. Surface expression is confirmed by flow cytometry.

 
III. Introduction
Host Cell: CHO
Expressed gene: GITRL
Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: F12K+10%FBS+400ug/ml hygromycin
Storage: Liquid nitrogen
Application(s): Ligand of GITR&Binding Assay,FACS
 

IV. Description of Host Cell Line

Organism: Hamster 
Tissue: Ovary
Disease: Hamster Chinese ovary
Morphology: Epitheloid cell
Growth Properties: Adherent
 
Ⅴ. Representative Data

Figure 1. Recombinant CHO cell constitutively expressing full length human GITRL. Surface expression is confirmed by flow cytometry.

 

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