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S154-hSTING-KI/NFκB-SEAP/THP-1

CBP74218

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I. Background
Different innate immune pathways converge to Stimulator of interferon genes (STING) and trigger type I interferon responses after recognition of abnormal nucleic acids in the cells. This non-redundant function renders STING a major player in immunosurveillance, and an emerging target for cancer and infectious diseases therapeutics.
 
II. Introduction
Host Cell: THP-1
Expressed gene: S154-hSTING-KI
Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: RPMI-1640+ 2 mM L-glutamine+ 25 mM HEPES+ 10%FBS+ 100 µg/ml Normocin+ Pen-Strep (100 U/ml-100 µg/ml)
Storage: Liquid nitrogen
 
III. Description of Host Cell Line
Organism: Homo sapiens, human
Tissue: peripheral blood
Disease: acute monocytic leukemia
Morphology: monocyte
Growth Properties: suspension
 
IV. Representative Data
 

 

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