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KRAS p.K117N Reference Standard

CBP10691

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Introduction 
Format Genomic DNA
Description KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways that plays a role in regulation of cell proliferation. KRAS mutations are identified in a wide range of cancers , including colorectal cancer, non-small cell lung cancer, and pancreatic cancer.
   
Technical Data 
DNA Change c.351A>C
AA Change p.K117N
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript NM_004985.5
Cosmic ID COSM19940
Chr position(GRCh37) chr12-25378647-T-G
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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