首页 /诊断试剂 /肿瘤标准品 /Mutation /AI-Edigene® KRAS p.A146T Reference Standard Plus

AI-Edigene® KRAS p.A146T Reference Standard Plus

CBP10555

询 价
索取COA
产品描述
产品数据库
Introduction 
Format Genomic DNA
Description KRAS A146T is an exon four mutation that does not lie within any known functional domains of the Kras protein (UniProt.org). A146T decreases Kras GTPase activity, increases phosphorylation of Mek and Erk, and is transforming in cell culture and xenografts (PMID: 19075190, PMID: 20570890).
   
Technical Data 
DNA Change c.436G>A
AA Change p.A146T
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript NM_033360.4
Cosmic ID COSM19404
Chr position(GRCh37) chr12:25378562
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

药靶模型联系方式: 华东销售经理:18240630236 全国销售经理:18066071954
诊断标准品联系方式: 华东销售经理:15000320447 华北销售经理:18131625521 华南销售经理:13484295986 华中&西南销售经理:13871580511 全国销售经理:13484295986

扫二维码

立即提交