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KRAS p.G12A Reference Standard

CBP10296

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索取COA
产品描述
产品数据库
Introduction 
Format Genomic DNA
Description KRAS G12A is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). G12A results in decreased Kras GTPase activity and increased activation of downstream signaling in cell culture (PMID: 23455880, PMID: 26037647).
   
Technical Data 
DNA Change c.35G>C
AA Change p.G12A
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 66.67%
Transcript ENST00000311936
Cosmic ID COSM522
Chr position(GRCh37) chr12:25398284
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture
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