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HRAS p.G12V Reference Standard

CBP10289

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索取COA
产品描述
产品数据库
Introduction 
Format Genomic DNA
Description HRAS G12V is hotspot mutation that lies within a GTP nucleotide binding region of the Hras protein (UniProt.org). G12V results in decreased Hras GTPase activity, loss of response to GTPase-activating proteins, leading to activation of downstream signaling pathways, and transFormation of cultured cells (PMID: 24224811, PMID: 21850009, PMID: 6330729).
   
Technical Data 
DNA Change c.35G>T
AA Change p.G12V
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000397596
Cosmic ID COSM483
Chr position(GRCh37) chr11:534288
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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