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FBXW7 p.R505S Reference Standard

CBP10283

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Introduction 
Format Genomic DNA
Description FBXW7 R505S lies within WD repeat 4 of the Fbxw7 protein (UniProt.org). R505S has been identified in sequencing studies (PMID: 27101000, PMID: 25670083), but has not been biochemically characterized and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Nov 2018).
   
Technical Data 
DNA Change c.1513C>A
AA Change p.R505S
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 75.00%
Transcript ENST00000281708
Cosmic ID COSM33763
Chr position(GRCh37) chr4:153247289
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8℃
Expiry 36 months from the date of manufacture

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