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AI-Edigene® NRAS p.G12S Reference Standard Plus

CBP10528

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索取COA
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Introduction 
Format Genomic DNA
Description NRAS G12S is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G12S confers a loss of function on Nras protein as indicated by increased Erk phosphorylation, increased cell preliferation, and is transforming in culture (PMID: 17823240).
   
Technical Data 
DNA Change: c.34G>A
AA Change p.G12S
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript NM_002524.5
Cosmic ID COSM563
Chr position(GRCh37) chr1:115258748
Buffer: Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purity Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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