SW948（人结肠癌细胞）
CBP60020
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| I. General information | |
| Synonyms: | SW948 |
| Species: | Homo sapiens, human |
| Tissue: | colon |
| Disease: | Dukes' type C, grade III, colorectal adenocarcinoma |
| Gender: | female,81 years, Caucasian |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| DNA Profile: | Amelogenin: X CSF1PO: 12 D13S317: 10,11 D16S539: 11,12 D5S818: 11 D7S820: 9,11 THO1: 6,9.3 TPOX: 8,11 vWA: 16,18 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
DMEM+10%FBS We strongly suggest to purchase the complete medium from Cobioer. |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | blood type O; Rh+ |
| Oncogene: | myc +; myb +; ras +; fos +; p53 +; sis -; abl -; ros -; src - |
| Genes Expressed: | carcinoembryonic antigen (CEA) 7 ng/106 cells/10 days; colon specific antigen (CSAp) 750 units in 0.5 mL cell sonicate; keratin |
| Cellular Products: | carcinoembryonic antigen (CEA) 7 ng/10 exp6 cells/10 days; colon specific antigen (CSAp) 750 units in 0.5 ml cell sonicate; keratin |
| Immunology: | Yes, in nude mice Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 107 cells. |
| Comments: | The cells are positive for keratin by immunoperoxidase staining. The line is positive for expression of c-myc, K-ras, H-ras, N-ras, myb and fos oncogenes.N-myc and sis oncogene expression were not detected. For more information, please contact Cobioer (4008-750-250). |
