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FGFR3-TACC3 [K650N] /BaF3

CBP73377

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I. Introduction
Cell Line Name: FGFR3-TACC3 [K650N] /BaF3
Host Cell: Ba/F3
Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Application: Anti-proliferation assay and PD assay
Freeze Medium: 90% FBS+10% DMSO
Complete Culture Medium: RPMI-1640+10%FBS
Mycoplasma Status: Negative
 
II. Background

FGFR3-TACC3 results from the fusion of FGFR3 and TACC3, demonstrating constitutive kinase activity, transforming activity in culture and ability to drive tumor growth in xenografts (PMID: 25294908, PMID: 22837387). FGFR3-TACC3 has been identified in lung adenocarcinoma and glioblastoma (PMID: 25294908, PMID: 22837387).

 
III. Representative Data

1.WB of FGFR3-TACC3 [K650N] /BaF3

2. Sanger of FGFR3-TACC3 [K650N] /BaF3

Figure 2. FGFR3-TACC3 [K650N] /BaF3 K650N

Figure 3. FGFR3-TACC3 [K650N] /BaF3 FGFR3-TACC3

3. Anti-proliferation assay

Figure 4. CTG Proliferation Assay of BaF3 FGFR3-TACC3 K650N Cells (C3).

药靶模型联系方式: 华东销售经理:18240630236 全国销售经理:18066071954
诊断标准品联系方式: 华东销售经理:15000320447 华北销售经理:18131625521 华南销售经理:13484295986 华中&西南销售经理:13871580511 全国销售经理:13484295986

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