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KRAS G12C-H95R/BaF3

CBP73347

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I. Introduction
Cell Line Name: KRAS G12C-H95R/BaF3
Host Cell: Ba/F3
Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Complete Culture Medium:  
Mycoplasma Status: Negative
 
II. Background

KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118).

 
III. Representative Data

1.Sanger of KRAS G12C-H95R/BaF3

Figure 1. KRAS G12C-H95R/BaF3 G12C

Figure 2. KRAS G12C-H95R/BaF3 H95R

2. Anti-proliferation assay

Figure 3. CTG Proliferation Assay of BaF3 KRAS G12C/H95R Cells (C11).

 

 

 

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