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FGFR2-BICC1/BaF3

CBP73268

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I. Introduction

Cell Line Name:

FGFR2-BICC1/BaF3

Host Cell:

Ba/F3

Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS

Mycoplasma Status:

Negative

 
II. Background

FGFR2-BICC1 results from the fusion of FGFR2 and BICC1, resulting in the ability to induce oligomerization, Fgfr kinase activity, Mapk signaling and transformation of cells in culture and in animal models (PMID: 23558953, PMID: 24122810, PMID: 28416604). FGFR2-BICC1 has been identified in intrahepatic cholangiocarcinoma (PMID: 25608663, PMID: 31899106).

 
III. Representative Data

1.WB of  FGFR2-BICC1/BaF3

2.Sanger of FGFR2-BICC1/BaF3

3. Anti-proliferation assay

Figure 3. CTG Proliferation Assay of BaF3 FGFR2-BICC1 Cells (C8).

  

药靶模型联系方式: 华东销售经理:18240630236 全国销售经理:18066071954
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