首页 /药靶模型 /药靶细胞 /激酶靶点 /TEL(ETV6)-JAK2/BaF3

TEL(ETV6)-JAK2/BaF3

CBP73117

询 价
留 言
产品描述
产品数据库
I. Introduction
Cell Line Name: TEL(ETV6)-JAK2/BaF3
Host Cell: Ba/F3
Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Application: This kit is useful for screening for small molecules displacing ATP from the JH2 domain of JAK2.
Freeze Medium: 90% FBS+10% DMSO
Complete Culture Medium: RPMI-1640+10%FBS+2ug/ml puromycin
Mycoplasma Status: Negative
 
II. Background

JAK2, Janus kinase 2, is a non-receptor protein tyrosine kinase that binds cytokine receptors to activate the interferon-alpha/beta/gamma pathway and is a member of the JAK/STAT signaling pathway (PMID: 15575979, PMID: 30092288). JAK2 mutations are observed in a variety of tumor types, including myeloproliferative neoplasms (PMID: 30074114), lymphoma (PMID: 29984752), leukemia (PMID: 29979407), and cervical cancer (PMID: 30003068). 

 
III. Representative Data

1.WB of BA/F3/TEL(ETV6)-JAK2

 

2. Anti-proliferation assay

 

Figure 2. CTG Proliferation Assay of BaF3 TEL-JAK2 (C1).

 

药靶模型联系方式: 华东销售经理:18240630236 全国销售经理:18066071954
诊断标准品联系方式: 华东销售经理:15000320447 华北销售经理:18131625521 华南销售经理:13484295986 华中&西南销售经理:13871580511 全国销售经理:13484295986

扫二维码

立即提交