hClaudin9(CLDN9)/4T1
CBPG0064
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| I. Background | |||
| CLDN9 (Claudin 9) is a Protein Coding gene. Diseases associated with CLDN9 include Deafness, Autosomal Recessive 116 and Hepatitis C Virus.This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. | |||
| II. Introduction | |||
| Host Cell: | 4T1 | ||
| Expressed gene: | hClaudin9(CLDN9) | ||
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) | ||
| Freeze Medium: | 90% FBS+10% DMSO | ||
| Culture Medium: | RPMI-1640+10%FBS+2ug/ml puromycin | ||
| Mycoplasma Testing: | Negative | ||
| Storage: | Liquid nitrogen | ||
| III. Description of Host Cell Line | |||
| Organism: | Mouse | ||
| Tissue: | Mammary gland | ||
| Morphology: | Epithelial | ||
| Growth Properties: | Adherent | ||
| IV. Representative Data | |||
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Figure 1. Recombinant hClaudin9(CLDN9)/4T1 stably expressing CLDN9. |
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