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FCGR2B/HEK293

CBP74078

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I. Background
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
 
II. Description
Recombinant HEK293 cells constitutively expressing human FCGR2B.
 
III. Introduction
Host Cell: HEK293
Expressed gene: FCGR2B(FcγRIIb)
Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s): CD32B, FCG2, Fc gamma receptor, Fcgamma receptor
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: DMEM+10%FBS+Hygromycin 100ug/ml
Mycoplasma Testing: Negative
Storage: Liquid nitrogen
Application(s): Binding Assay,FACS
 
IV. Description of Host Cell Line
Organism: Human
Tissue: kidney
Morphology: Epitheloid cell
Growth Properties: Adherent
 
Ⅴ. Representative Data

Figure 1.Recombinant HEK293 cells constitutively expressing FCGR2B(FcγRIIb).

 

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