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hIL19/IL20/IL24 Triple Effector Reporter Cell

CBP74223

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I. Background
IL-19, IL-20, and IL-24 are closely related cytokines that belong to the IL-20 subfamily and play an important role in the protection of barrier tissues. They share the heterodimeric IL-20 type I and type II receptors composed of the IL-20Rα and IL-20Rβ chains, and IL-22Rα1 and IL-20Rβ chains, respectively.
 
II. Introduction
Expressed gene: hIL19/IL20/IL24
Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: N/A
Mycoplasma Testing: Negative
Storage: Liquid nitrogen
Application(s): Functional(Report Gene) Assay
 
III. Representative Data

Figure 1. Dose Response of Ligands in hlL19/IL20/IL24 Triple Effector Reporter Cells (C16).

Figure 2. Inhibition of Human lL20-induced Reporter Activity by hlL20 Neutralization Ab in hlL19/lL20/IL24 Triple Effector Reporter Cells (C16).

 

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