首页 /药靶模型 /药靶细胞 /免疫治疗 /SIRPɑ Effector Reporter Cell

SIRPɑ Effector Reporter Cell

CBP74122

询 价
索取Protocol
产品描述
产品数据库
I. Background
SIRP alpha protein, or Signal regulatory proteinalpha (SIRP-α), also known as Tyrosine protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NM_080792, a.a. 27-370, with C-terminal Avi and His tags, MW 40.3 kDa*. This SIRP alpha protein acts as a receptor for CD47; a.a. 27-370 correspond to the extracellular portion of SIRP-α. *Note: SIRP-α is heavily glycosylated, resulting in higher molecular weight. 
 
II. Introduction
Expressed gene: SIRPɑ
Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s): SIRP alpha protein, sirpa protein, sirp-a protein, SIRPα, CD172a, Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, 71138-1, 71138-2
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: RPMI-1640+10%FBS+1ug/ml puromycin+300ug/ml hygromycin
Mycoplasma Testing: Negative
Storage: Liquid nitrogen
Application(s): Functional(Report Gene) Assay
 
III. Representative Data

Figure 1. Dose response of Sirpɑ Blocking Antibodies in SIRPɑ Effector Reporter Cells With CD47+ Target Cells.



 

Figure 2. Dose response of CD47 Blocking Antibodies in SIRPɑ Effector Reporter Cells With CD47+ Target Cells.

药靶模型联系方式: 华东销售经理:18240630236 全国销售经理:18066071954
诊断标准品联系方式: 华东销售经理:15000320447 华北销售经理:18131625521 华南销售经理:13484295986 华中&西南销售经理:13871580511 全国销售经理:13484295986

扫二维码

立即提交